This is why there is a voting system.
It is pretty obvious to be able to tell, if a score is changed or infinite lives, just by reading the manual.
As long as all of the precautions are performed - start recording before console turn on, prove no game genie codes or save state capabilities are possible, and the rules for each individual game... there's zero difference between a rom running on a console, whether it be a masked rom, an eeprom, or a flash cart.